First, you have to make sure you have a free port available on your motherboard. Admittedly, I'm not particularly familiar with Mac's, so I would suggest looking in your computer manual. If you've lost the manual, you can find it online. Could you also provide a link to the exact PCIe Expansion card you are talking about? Inateck makes quite a few of those. Just note that you will probably be significantly limited in your bandwidth if you plan on populating all four USB 3.0 ports.
One USB 3.0 has a maximum bandwidth of 5 Gbit/s, so that means the card could use up to 20 Gbit/s in total. A PCIe x1 port will provide 4 Gbit/s, so if the card is x1 then you will be bottlenecked by using even 1 of the four USB 3.0 ports. A PCIe x4 has four times the throughput as an x1, so 16 Gbit/s, which could still be a limitation. A PCIe x8 provides a 32 Gbit/s transfer rate. The only problem with this is that you are wasting 12 Gbit/s (which could give you 2 extra USB 3.0 ports), and x8 cards aren't very common. Just note that if you plan on using a USB 2.0 device(s) in the card you should be fine with even a PCIe x1, as one USB 2.0 uses about 1/10 of the bandwidth of USB 3.0 (500 Mbit/s, or 2 Gbit/s if all four ports are being used). In fact, you could probably cram 8 USB 2.0 ports into one PCIe x1 card (or 16 USB 1.0).
Caldigit USB3 card. The best card out of 3. Software driver is very stable and Lexar highly recommend their card. The card I am using is their. The Allegro Pro USB 3.0 PCIe card features a PCIe 2.0 x4 bus interface to take advantage of one of your computer’s fast expansion card slots. This card installs easily into any x4 PCI Express® (PCIe) slot that supports a full-height card, features hot-pluggable and hot-swappable device connection support with automatic device configuration, and works with all USB-IF compliant USB 3.0 and USB 2.0 peripherals.
How to format a USB stick on a Mac Sometimes you need to format (completely erase) an USB stick to restore it to its full capacity. Here's how to format an USB stick on a Mac. Disk Utility, a free application included with the Mac operating system, is a multipurpose, easy-to-use tool for working with hard drives, SSDs, and disk images. Among other things, Disk Utility can erase, format, repair, and partition hard drives and SSDs, as well as create RAID arrays.
Dunno exactly what you'll be using this capture device for, but you should know that HDMI cables use anywhere from 5 Gbit/s to 18 Gbit/s, so you could be severely limiting yourself by going with USB. (Although I believe that if you are only doing 1080p @ 60 Hz you will *barely* be fine). Biography for full specs.